Red Eye w/Greg Gutfeld is an American late-night/early-morning satirical talk show on the Fox News Channel, airing at 3:00 am ET Tuesday through Saturday, 11:00 pm Saturday, and 2:00 am Sunday. The show features panelists and guests discussing the latest news in politics, pop culture, entertainment, business, sports, and religion. The show is hosted by Greg Gutfeld, a self-described libertarian, who is a former Maxim UK editor.

In 2007, VH1 contributor Michelle Collins described watching Red Eye w/Greg Gutfeld as, "You almost feel like you’re going out and not going out. It’s like being at a bar with your friends and hearing all their opinions—while laying in bed eating Snackwell cookies."